site stats

Regulon connection specificity index

WebJul 20, 2024 · The activity of each regulon in the pseudo-cell was scored using the R package “AUCell.” Regulon modules were identified using the Connection Specificity Index. Multiplex immunofluorescence staining in GBM samples from the Xiangya cohort. Paraffin sections were deparaffinized. After antigen retrieval, sections were blocked with 3% H 2 O … WebMay 23, 2024 · To identify master regulons, we calculated cell-type specificity scores for each regulon in every cell type using the RSS method implemented in calcRSS function in …

Mapping Mouse Cell Network Atlas with Regulon Activity (A) …

WebJun 3, 2024 · Calculate connection specificity index (CSI) for all regulons. The final statistics that we want to calculate is the connection specificty index. The CSI is a major … black mass online subtitrat https://camocrafting.com

The Clinical Significance and Potential Molecular Mechanism ... - Hindawi

Web利用SCENIC软件，可以有效识别Regulon调控子以及每个细胞的Regulon活性得分（RAS, regulon activity score）；通过计算Regulon特异性得分（RSS, Regulon specificity score） … WebMay 23, 2024 · To identify master regulons, we calculated cell-type specificity scores for each regulon in every cell type using the RSS method implemented in calcRSS function in the R package SCENIC. RSS algorithms were developed based on Jensen–Shannon divergence by Suo et al. (2024 ) and have been proved to be an effective method to identify cell-type … Web(C) Sankey plot demonstrates the distribution pattern of top 20 specific regulons for each cell type in the representative regulon modules. CSI, connection specificity index. Source publication garage fisher price

HIF1A modulate glycolysis function to governs mouse ovarian ...

Category:A scalable SCENIC workflow for single-cell gene regulatory ... - Nature

Tags:Regulon connection specificity index

Regulon connection specificity index

A scalable SCENIC workflow for single-cell gene regulatory ... - Nature

WebAug 4, 2024 · The regulon modules based on the regulon crosstalk (regulon-to-regulon correlation) were determined by the Connection Specificity Index (CSI) that ranks the regulon significance and mitigates the effects of nonspecific interactions. The analysis of the primary and metastatic groups led to 65 regulons across six regulon modules (Figure … WebSep 21, 2024 · To highlight the regulon crosstalk and regulation across integrated cell atlas, we performed regulon-to-regulon correlation using Connection Specificity Index (CSI) …

Regulon connection specificity index

Did you know?

WebMar 1, 2024 · compared the difference of RAS scores of each regulon by the Connection Specificity Index 29 (CSI) (Extended Data Fig. 4a-f ). Interes ting, 209 regulons and 263 regulons are WebMar 14, 2024 · Identified specific regulators of the maintenance of TREM2 + macrophage identity. (A) Identification of regulon modules based on the regulon connection …

WebNov 6, 2024 · Regulon modules were identified based on the Connection Specificity Index (CSI) (Fuxman Bass et al., 2013), which is a context-dependent measure for identifying … WebHeatmap of hierarchically clustered connection specificity index of regulon and 16 regulon modules were discerned.

WebJun 19, 2024 · Fig. 10: Regulon specificity score for each PBMC subtype. The top five regulons in each cell type are highlighted in red and labeled on the plot. The specificity … WebA tag already exists with the provided branch name. Many Git commands accept both tag and branch names, so creating this branch may cause unexpected behavior.

WebFeb 24, 2024 · CSI, connection specificity index. To further understand the functional relationships between different TFs and assess whether different TFs could act cooperatively to regulate cell fate, we quantified the functional similarities among …

WebJun 19, 2024 · Fig. 10: Regulon specificity score for each PBMC subtype. The top five regulons in each cell type are highlighted in red and labeled on the plot. The specificity score is shown on the y axis. garage fishing rod holderWebMay 18, 2024 · A single regulon interpretation. (1) Each regulon is named by the cell type index and regulon number. A regulon is a cell-type-specific regulon (CTSR) if the adjusted P-value of the regulon specificity score (RSS) is less than 0.05. CTSRs are in orange, and insignificant regulons are in gray. black mass on liverWebAug 7, 2024 · Finally, the regulon-activity matrix for all samples was used for PCA, t-SNE, connective specificity index (CSI) network 14 (visualized by Cytoscape v.3.5.1 37) and … garage fishing rod rack