Ifn-alpha 1
All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor that consists of IFNAR1 and IFNAR2 chains. Type I IFNs are found in all mammals, and homologous (similar) molecules have been found in birds, reptiles, amphibians and fish species. Meer weergeven The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses. In the human genome, a cluster of thirteen functional IFN genes is … Meer weergeven IFN-α and IFN-β are secreted by many cell types including lymphocytes (NK cells, B-cells and T-cells), macrophages, fibroblasts, endothelial cells, osteoblasts and others. They stimulate both macrophages and NK cells to elicit an anti-viral … Meer weergeven In cancer From the 1980s onward, members of type-I IFN family have been the standard care as immunotherapeutic agents in cancer therapy. In particular, IFNα has been approved by the US Food and Drug Administration (FDA) … Meer weergeven Interferonopathies are a class of hereditary auto-inflammatory and autoimmune diseases characterised by upregulated … Meer weergeven The mammalian types are designated IFN-α (alpha), IFN-β (beta), IFN-κ (kappa), IFN-δ (delta), IFN-ε (epsilon), IFN-τ (tau), IFN-ω … Meer weergeven Therapeutics From the 1980s onward, members of type-I IFN family have been the standard care as immunotherapeutic agents in cancer therapy. In particular, IFNα has been approved by the US Food and Drug Administration (FDA) … Meer weergeven One of the major limiting factors in the efficacy of type I interferon therapy are the high rates of side effects. Between 15% - 40% of people undergoing type 1 IFN treatment … Meer weergeven WebIFN-α (PDB: 1RH2 ). インターフェロン ( 英: Interferon 、略号: IFN )とは、 動物 体内で 病原体 (特に ウイルス )や 腫瘍 細胞 などの異物の侵入に反応して細胞が 分泌 す …
Ifn-alpha 1
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WebInvitrogen Anti-IFN alpha Polyclonal, Catalog # PA5-86767. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 100 µL purified antibody (1 mg/mL). Web干扰素. 干扰素 (英語: Interferon; IFNs; / ˌɪn ( t) ərˈfɪrˌɑːn / [1] )為一組 细胞信号传送 蛋白 [2] ,是在 动物 细胞 在受到某些 病毒 感染 后分泌的具有“触发”免疫系统防御病毒功 …
WebInterferone (IFN, von lateinisch interferre ‚eingreifen‘, ‚sich einmischen‘) sind Proteine oder Glykoproteine, die eine immunstimulierende, vor allem antivirale und antitumorale … WebInterferon(IFN) alpha and IFN beta apparently share the same receptor structure, the type I IFN receptor, which consist of at least two subunits. The subunits are referred to as IFN …
WebL'IFN-α recombinant est utilisé en thérapie antivirale (hépatites B et C, sarcome de Kaposi associé au sida) et en thérapie anti-cancéreuse (cancer du rein, mélanome, leucémie à … Web13 sep. 2011 · Biological activity. Interferon alpha 1 (ab48750) has the activity of 4 X 10 5 unit/mg (or 4 X 10 5 unit/ml). This activity has been tested by evaluating anti-proliferation …
Web干擾素. 干擾素 (英語: Interferon; IFNs; / ˌɪn ( t) ərˈfɪrˌɑːn / [1] )為一組 細胞信號傳送 蛋白 [2] ,是在 動物 細胞 在受到某些 病毒 感染 後分泌的具有「觸發」免疫系統防禦病毒功能的 宿主 特異性 醣蛋白 (本身並不直接與病毒作用)。. 細胞感染病毒後 ...
WebRecombinant Human Interferon Alpha A (Alpha 2a) obtained from human leukocyte mRNA expressed in E.coli. IFN-Alpha 2a is one of the many interferon alpha subtypes belonging … bringing back the villageWebIFN-α1 (interferon α 1) is a type 1 interferon. Human IFN-a1 is a 19.3kDa protein containing 166 amino acid residues. IFN-α1 belongs to the type I interferon (IFN) family and is … bringing back tobacco from hungaryWebLas proteínas IFN-α se producen principalmente por las células dendríticas plasmacitoides (pDCs). Están principalmente involucradas en la inmunidad innata contra la infección … bringing back to health crossword clue