WebDrug resistance is a common and serious problem in the treatment of epilepsy, affecting about 1in 3 patients. It is associated with increased morbidity and increased risk of … WebCabazitaxel is a novel tubulin-binding taxane that differs from docetaxel because of its poor affinity for P-glycoprotein (P-gp), an ATP-dependent drug efflux pump. Cancer cells that express P-gp become resistant to taxanes, and the effectiveness of docetaxel can be limited by its high substrate affinity for P-gp.
Infection and Drug Resistance Taylor & Francis Online
WebAntimicrobial resistance happens when germs like bacteria and fungi develop the ability to defeat the drugs designed to kill them. Resistant infections can be difficult, and … Web13 de abr. de 2024 · Resistance to anticancer drugs is a multifactorial phenomenon that occurs through multiple mechanisms. Subpopulations of cancer cells with various genetic composition co-existing in primary tumors have different sensitivity to chemotherapy or targeted drugs, such that initial treatment can eliminate only a fraction of cancer cells … how to say dam in german
Stop the Spread of Superbugs NIH News in Health
WebNational Center for Biotechnology Information WebHá 6 horas · Published: Apr. 14, 2024 at 6:52 AM PDT Updated: moments ago. WASHINGTON (AP) — The Biden administration and a drug manufacturer asked the Supreme Court on Friday to preserve access to an abortion drug free from restrictions imposed by lower court rulings, while a legal fight continues. The Justice Department and … Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved. Antimicrobial resistance and antineoplastic resistance challenge clinical care and drive research. When an organism is resistant to more than one drug, it is said to be multidrug-resistant. how to say damn in japanese