WebJan 16, 2012 · CLRs in the Dectin-2 group are similar in structure to those of the Dectin-1 group, with one notable exception: the Dectin-2 family of CLRs contains a short cytoplasmic domain. They are ... WebDectin‐1 and Dectin‐2 have been shown to promote secretion of IgA in the gut and agonists of those receptors could constitute interesting vaccine adjuvants to promote the mucosal adaptive response. 73 In mice, Mincle contributes to the establishment of a local tonic Th17 response that prevents microbiota from translocating into the ...

The Dectin-2 family of C-type lectin-like receptors: an update

WebFeb 1, 2024 · Dectin-2 has been implicated in the defense against numerous pathogens, including C. albicans, C. neoformans, A. fumigatus, Saccharomyces cerevisiae, Paracoccidioides brasiliensis, Histoplasma capsulatum, Microsporum audouinii, Trichophyton rubrum, Mycobacterium tuberculosis, and Schistosoma mansoni ( 75, 78, 80 ). WebDec 6, 2016 · Here, we show that Dectin-2, a C-type lectin receptor (CLR) family of innate receptors, is critical for the suppression of liver metastasis of cancer cells. We provide … david oguoguo okeke

Dectin-2 family of C-type lectin-like receptors: an update ...

WebDectin-1 and Dectin-2 are type II transmembrane proteins of the C-type lectin family with single carbohydrate recognition domains (CRDs) in their extracellular region. They are … Web2024 CiteAb Awards - View the winners now! ... Search WebAug 7, 2009 · The Dectin-2 family are multifunctional receptors, and have been shown to be important in both homeostasis and immunity. Many can act as PRRs and they … bayu lagenda