WebDec 19, 2011 · The platinum-based chemotherapy agents cisplatin, carboplatin, and oxaliplatin, used to treat a huge number of cancers including the lung, upper and lower GI, ovarian, and germ cell tumours, are a common cause of renal tubular and glomerular damage, which can be treatment-limiting. WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare …
UpToDate
WebNov 15, 2024 · Nonalcoholic fatty liver disease (NAFLD) is the most common form of liver disease in the United States, affecting up to 30% of adults. There are two forms of NAFLD: nonalcoholic fatty liver (NAFL ... WebNov 1, 2015 · Cirrhosis Insulin resistance Drug-induced NAFLD Drug-induced NASH Introduction Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases of western world. It is defined as fat deposition of hepatocytes exceeding 5% of the hepatocytes histologically in individuals with little or no alcohol consumption. chronic lyme treatment
Cisplatin - The Penicillin of Cancer
WebJul 20, 2024 · Five patients (8.8%) required discontinuation of pembrolizumab because of irAEs, all of which occurred during concurrent chemoradiotherapy; 98.3% of patients completed the full planned treatment dose (70 Gy) of radiotherapy without any delays ≥ 5 days; 88.1% of patients completed the goal cisplatin dose of ≥ 200 mg/m2. WebFeb 11, 2024 · Cirrhosis often has no symptoms until liver damage is severe. When symptoms do occur, they may include: Fatigue. Easily bleeding or bruising. Loss of … WebJun 22, 2024 · Limited-stage disease — The most commonly used combination of chemotherapy drugs for patients with limited-stage small cell lung cancer is cisplatin plus etoposide. Due to the high rate of side effects associated with cisplatin, a related drug called carboplatin is frequently used in its place and appears to be equally effective in … derek hough live dance tour